Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure-Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor Alexander J. Bridges,Hairong Zhou,et al. J. Med. Chem 1996;39:267-276
PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner. M Bos, J Mendelsohn, Y M Kim, et al. Clin Cancer Res 1997;3:2099-2106
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