AMG 706, an Oral, Multikinase Inhibitor that Selectively Targets Vascular Endothelial Growth Factor,Platelet-Derived Growth Factor, and Kit Receptors, Potently Inhibits Angiogenesis and Induces Regression in Tumor Xenografts Angela Coxon, Charlie Starnes, et al. Cancer Res 2006;66:8715-8721
Broad Antitumor Activity in Breast Cancer Xenografts by Motesanib, a Highly Selective, Oral Inhibitor of Vascular Endothelial Growth Factor, Platelet-Derived Growth Factor,and Kit Receptors Tammy Bush, Douglas Saffran, et al. Clin Cancer Res 2009;15:110-118
Motesanib Diphosphate in Progressive Differentiated Thyroid Cancer Steven I. Sherman, Lori J. Wirth,et al. N Engl J Med 2008;359:31-42
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.