Indirubin, the active constituent of a Chinese antileukaemia medicine,inhibits cyclin-dependent kinases Ralph Hoessel,Sophie Leclerc,et al. NATURE CELL BIOLOGY MAY 1999;1:60-67
Indirubins Inhibit Glycogen Synthase Kinase-3b and CDK5/P25,Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer’s Disease Sophie Leclerc,Matthieu Garnier,et al. THE JOURNAL OF BIOLOGICAL CHEMISTRY 2001;276:251–260
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.