• Catalog Number:

  E011237-1

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 988 (I-K-SP-F-V).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human

• SwissProtNo:

  P38398

• Applications:

  IF:1:100~1:200

• Specificity Sensitivity:

  BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.

• References:

  Scully, R. and Livingston, D.M. (2000) Nature 408, 429-432. Tutt, A. and Ashworth, A. (2002) Trends Mol. Med. 8, 571-576. Okada, S. and Ouchi, T. (2003) J. Biol. Chem. 278, 2015-2020.

Immunofluorescence staining of methanol-fixed HeLa cells using BRCA1 (phospho-Ser988) antibody (E011237, Red).