Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 1007 (K-E-YP-Y-K).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Reactivity:
Human, Mouse, Rat
SwissProtNo:
O60674
Applications:
IHC: 1:50~1:100
Specificity Sensitivity:
JAK2 (phospho-Tyr1007) antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 1007.
References:
James C, et al. (2005) Nature. 434(7037): 1144-1148.
Argetsinger LS, et al. (2004) Mol Cell Biol. 24(11): 4955-4967.
Ungureanu D, et al. (2002) Mol Cell Biol. 22(10): 3316-3326.
Xie S, et al. (2001) Oncogene. 20(43): 6188-6195.
P-Peptide - +
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using JAK2 (phospho-Tyr1007) antibody (E011151).