• Catalog Number:

  E011102-1

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 396 (Y-K-SP-P-V).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P10636

• Applications:

  WB: 1:500~1:1000

• Specificity Sensitivity:

  Tau (phospho-Ser396) antibody detects endogenous levels of Tau only when phosphorylated at serine396.

• References:

  Puig B, et al. (2005) Acta Neuropathol (Berl). 110(3):261-268. DeGiorgis JA, et al. (2005) J Proteome Res. 4(2): 306-315. Alonso Adel C, et al. (2004) J Biol Chem. 279(33): 34873-34881. Kyriakis J M, et al. (1994) Nature. 369: 156-160.

Western blot analysis of extract from mouse brain tissue using Tau (Ab-396) antibody (E021093, Lane 1 and 2) and Tau (phospho- Ser396) antibody (E011102, Lane 3 and 4).