Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from human Glutamate receptor 2 around the phosphorylation site of serine 880 (I-E-SP-V-K) (CYNVYGIESVKI).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Glutamate receptor 2 (phospho-Ser880) antibody detects endogenous levels of Glutamate receptor 2 only when phosphorylated at serine 880.
References:
Kenneth J. Seidenman, J. Neurosci., Oct 2003; 23: 9220.
Baosong Liu, J. Neurosci., May 2006; 26: 5309 - 5319.
Jie Fu, J. Neurosci., Aug 2003; 23: 7592.
Jose L. Perez, J. Neurosci., Aug 2001; 21: 5417.
All Sites:
Human: Ser880; Mouse: Ser880; Rat: Ser880
P-peptide - +
Immunohistochemical analysis of paraffin-embedded human brain tissue using Glutamate receptor 2 (phospho-Ser880) antibody.
Western blot analysis of extracts from mouse brain, using Glutamate receptor 2 (phospho-Ser880) antibody.