• Catalog Number:

  E1A1217A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human MRE11 around the phosphorylation site of serine 264 (Y-I-SP-Q-P).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human

• SwissProtNo:

  P49959

• Applications:

  WB: 1:500~1:1000 ELISA: 1:1000

• Other Names:

  Double-strand break repair protein MRE11A, HNGS1, MRE11, MRE11 homolog 1, MRE11A, MmMRE11A

• Specificity Sensitivity:

  MRE11 (Phospho-Ser264) antibody detects endogenous levels of MRE11 only when phosphorylated at serine 264.

• References:

  Petrini J.H.J., Genomics 29:80-86(1995). Petrini J.H.J., Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. Chamankhah M., Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.

• All Sites:

  Human: Ser264

Western blot analysis of extracts from 3T3 cells, treated with forskolin (40nM, 30mins), using MRE11 (Phospho-Ser264) antibody.