• Catalog Number:

  E1A1025A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Caspase 1 around the phosphorylation site of serine 376 (R-F-SP-F-E).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  P29466

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

• Other Names:

  CASP-1, EC 3.4.22.36, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, caspase-1, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

• Specificity Sensitivity:

  Caspase 1 (Phospho-Ser376) antibody detects endogenous levels of Caspase 1 only when phosphorylated at serine 376.

• References:

  Thornberry N.A., Nature 356:768-774(1992). Feng Q., Genomics 84:587-591(2004). Agostini L., Immunity 20:319-325(2004).

• All Sites:

  Human: Ser376; Mouse: Ser374

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Caspase 1 (Phospho-Ser376) antibody. Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) antibody.