Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human p70 S6 Kinase around the phosphorylation site of serine 427 (K-F-SP-F-E).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
EC 2.7.11.1; kinase p70S6K; KS6B1; p70-S6K; P70-S6K; Ribosomal protein S6 kinase; Ribosomal protein S6 kinase, 70kDa, polypeptide 1; RPS6KB1; S6K
Specificity Sensitivity:
p70 S6 Kinase (Ab-427) antibody detects endogenous levels of total p70 S6 Kinase protein.
References:
Grove J., Mol. Cell. Biol. 11:5541-5550(1991).
Gout I., J. Biol. Chem. 273:30061-30064(1998).
Olsen J.V., Cell 127:635-648(2006).
Peptide - +
Immunohistochemistry analysis of paraffin-embedded human brain tissue using p70 S6 Kinase (Ab-427) antibody.
Western blot analysis of extracts from 293 cells, using p70 S6 Kinase (Ab-427) antibody.