http://en.wikipedia.org/wiki/Vadimezan http://en.wikipedia.org/wiki/Vadimezan ;
Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development. Phillips RM. Biochem Pharmacol. 1999 Jul 15;;58(2):303-10.
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis. Roberts ZJ, J Exp Med. 2007 Jul 9;;204(7):1559-69.
Antivascular therapy of cancer: DMXAA. Baguley BC. Lancet Oncol. 2003 Mar;;4(3):141-8.
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.