R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation Sylvia Braselmann, Vanessa Taylor, et al. JPET 2006;319:998–1008
The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets J.C.SPALTON,J.MORI,et al. J Thromb Haemost 2009;7: 1192–1199
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.