Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation Kathy Kamath, Diane Braguer, et al. Mol Cancer Ther 2003;2:1303-1311
4 The Natural Products Epothilones A and B as Lead Structures for Anticancer Drug Discovery: Chemistry, Biology,and SAR Studies KARL-HEINZ ALTMANN,ANDREAS FLORSHEIMER,et al. Progress in Medicinal Chemistr 2004;42:171-205
http://en.wikipedia.org/wiki/Epothilone http://en.wikipedia.org/wiki/Epothilone ;
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.