YM155, a Novel Small-Molecule Survivin Suppressant,Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts Masahiro Takeuchi, Isao Kinoyama, et al. Cancer Res 2007;67:8014-8021
Multicenter Phase II Trial of YM155, a Small-Molecule Suppressor of Survivin, in PatientsWith Advanced,Refractory, Non–Small-Cell Lung Cancer Giuseppe Giaccone, Petr Zatloukal,et al. J Clin Oncol 2009;27:4481-4486.
Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin Anthony W. Tolcher, Alain Mita,et al. J Clin Oncol 2008;26:5198-5203
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.