Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Scales SJ et al. Trends Pharmacol Sci. 2009 Jun;30(6):303-12.
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449 Charles M. Rudin, Christine L. Hann,et al. N Engl J Med 2009;361:1173-8
Hedgehog Pathway Inhibitor HhAntag691 Is a Potent Inhibitor of ABCG2/BCRP and ABCB1/Pgp1 Yimao Zhang,John Laterra,et al. Neoplasia January 2009;11:96–101
Mechanisms of Hedgehog pathway activation in cancer and implications for therapy Suzie J. Scales and Frederic J. de Sauvage Trends in Pharmacological Sciences 2009;30:303-312
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