50 mg/mL stocks in DMSO with 10% 2-hydroxyl-propyl-β-cyclodextrine/PBS
Dosages
50 mg/kg
Administration
Administered via i.p. injection at 10 μL/g of body weight
Storage/Stability:
at -20℃ 2 years
References:
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1 Keith A. Menear,Claire Adcock,et al. J. Med. Chem 2008;51:6581–6591
Menear KA, et al. J Med Chem, 2008, 51(20), 6581-6591.
Evers B, et al, Clin Cancer Res, 2008, 14(12), 3916-3925.
Rottenberg S, et al, Proc Natl Acad Sci U S A, 2008, 105(44), 17079-17084.
Weston VJ, et al, Blood, 2010, 116(22), 4578-4587.
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.