Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human beta Amyloid A4 around the phosphorylation site of threonine 743.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Reactivity:
Human, Mouse
SwissProtNo:
P05067
Applications:
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
Specificity Sensitivity:
beta Amyloid A4 (Ab-743) antibody detects endogenous levels of total beta Amyloid A4 protein.
References:
Muresan Z, Muresan V (2004) Hum Mol Genet 13, 475-88.
Selkoe, D.J. (1996) J. Biol. Chem. 271, 18295-18298.
Caporaso, G.L. et al. (1992) Proc. Natl. Acad. Sci. USA 89, 3055-3059.
Hung, A.Y. and Selkoe, D.J. (1994) EMBO J. 13, 534-542.
Suzuki, T. et al. (1994) EMBO J. 13, 1114-1122.
Ando, K. et al. (1999) J. Neurosci. 19, 4421-4427.
Iijima, K.I. et al. (2000) J. Neurochem. 75, 1085-1091.
Immunohistochemical analysis of paraffin- embedded human spinal cord tissue using beta Amyloid A4 (Ab-743/668) Antibody (E022057).