Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307(T-E-SP-I-T).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Reactivity:
Human, Mouse, Rat
SwissProtNo:
P35568
Applications:
IHC: 1:50~1:100
Specificity Sensitivity:
IRS-1 (Ab-307) antibody detects endogenous levels of total IRS-1 protein.
References:
Steppan CM, et al. (2005) Mol Cell Biol; 25(4): 1569-1575
Tuncman G, et al. (2006) Proc Natl Acad Sci U S A; 103(28): 10741-10746
Shoelson SE, et al. (2006) J Clin Invest; 116(7): 1793-1801