• Catalog Number:

  E011549-1

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human c-Cbl around the phosphorylation site of tyrosine 770 (T-E-YP-M-T).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human

• SwissProtNo:

  P22681

• Applications:

  IHC: 1:50~100

• Specificity Sensitivity:

  c-Cbl (phospho-Tyr700) Antibody detects endogenous levels of c-Cbl only when phosphorylated at tyrosine 770.

• References:

  Blake, T.J. et al. (1991) Oncogene 6, 653-657. Thien, C.B. and Langdon, W.Y. (1998) Immunol. Cell Biol. 76, 473-482. Kamei, T. et al. (2000) Int. J. Oncol. 17, 335-339. Hunter, C. et al. (1999) J. Biol. Chem. 274, 2097-2106.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Cbl (phospho-Tyr700) Antibody (E011549).