• Catalog Number:

  E011320-2

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human SHP-2 around the phosphorylation site of tyrosine 580 (R-V-YP-E-N).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  Q06124

• Applications:

  IHC: 1:50-1:100

• Specificity Sensitivity:

  SHP-2 (Phospho-Tyr580) antibody detects endogenous levels of SHP-2 only when phosphorylated at tyrosine 580.

• References:

  Ferjoux G, et al. (2003) Mol Biol Cell. 2003 ; 14(9): 3911-3928. Shi ZQ, et al. (2000) Mol Cell Biol ; 20(5): 1526-1536. Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96(17): 9677-9682 Mañes S, et al. (1999) Mol Cell Biol ; 19(4): 3125-3135. Oh ES, et al. (1999) Mol Cell Biol; 19(4): 3205-3215.

P-Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using SHP-2 (Phospho-Tyr580) antibody (E011320).