• Catalog Number:

  E011125-2

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human c-Abl around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  P00519

• Applications:

  IHC: 1:50~1:100

• Alter Name:

  c-ABL, ABL1, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, p150

• Specificity Sensitivity:

  c-Abl (phospho-Tyr412) antibody detects endogenous levels of c-Abl only when phosphorylated at tyrosine 412.

• References:

  Kawai H, et al. (2002) Mol Cell Biol 22(17): 6079-6088. Vogt Sionov R, et al. (2001) Mol Cell Biol 21(17): 5869-5878. Kharbanda S, et al. (2000) Mol Cell Biol 20(14): 4979-4989. Yoshida K, et al. (2002) Mol Cell Biol 22(10): 3292-3300.

• All Sites:

  Human: Tyr412; Mouse: Tyr412

P-Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Abl (phospho-Tyr412) antibody (E011125).