• Catalog Number:

  E011122-2

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human ATM around the phosphorylation site of serine 1981 (E-G-SP-Q-S).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  Q13315

• Applications:

  IHC: 1:50~1:100

• Alter Name:

  A-T, mutated, Ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, Serine-protein kinase ATM, kinase ATM

• Specificity Sensitivity:

  ATM (phospho-Ser1981) antibody detects endogenous levels of ATM only when phosphorylated at serine 1981.

• References:

  Gupta A. et al. (2005) Mol Cell Biol. 25(12): 5292-5305. Bernstein JL. et al. (2002) Breast Cancer Res. 4(6): 249-252. Silverman J. et al. (2004) Genes Dev. 18(17): 2108-2119. Nakada D. et al. (2003) Nucleic Acids Res. 31(6): 1715-1724.

• All Sites:

  Human: Ser1981; Mouse: Ser1987

P-Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ATM (phospho-Ser1981) antibody (E011122).