• Catalog Number:

  E011107-2

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of threonine 181 (P-K-TP-P-P).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P10636

• Applications:

  WB: 1:500~1:1000 IHC:1:50-100

• Specificity Sensitivity:

  Tau (phospho-Thr181) antibody detects endogenous levels of Tau only when phosphorylated at threonine 181.

• References:

  Puig B, et al.(2005) Acta Neuropathol (Berl). 110(3):261-268. Pérez M, et al.(2005) Neuroscience. 130(2): 339-347. Fellgiebel A, et al.(2004) Biol Psychiatry. 56(4): 279-283. del C Alonso A, et al.(2004) J Biol Chem. 279(33): 34873-34881.

Immunohistochemical analysis of paraffin-embedded rat hippocampal region tissue from a model with Alzheimer’s Disease using Tau (phospho-Thr181) antibody (E011107)

Western blot analysis of extract from mouse brain tissue using Tau (Ab-181) antibody (E021096, Lane 1 and 2) and Tau (phospho-Thr181) antibody (E011107, Lane 3 and 4).