• Catalog Number:

  E1A0959A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human NMDA or NR2A/B around the phosphorylation site of tyrosine1246/1252 (N-L-YP-D-I).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  Q12879/Q13224

• Applications:

  IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

• Other Names:

  2A, N-methyl-D-aspartate receptor subtype 2A, NMDAR2AGlutamate [NMDA] receptor subunit epsilon 1, NMDE1, NME1, NR2A; GRIN2B, Glutamate [NMDA] receptor subunit epsilon 2 precursor, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDE2, NME2, NR2B, NR3, hNR3

• Specificity Sensitivity:

  NMDA/NR2A/B (Phospho-Tyr1246/1252) antibody detects endogenous levels of NMDA or NR2A/B only when phosphorylated at tyrosine 1246/1252.

• References:

  Hess S.D., J. Pharmacol. Exp. Ther. 278:808-816(1996). Olsen J.V., Cell 127:635-648(2006). Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).

• All Sites:

  Human: Tyr1246/1252; Mouse: Tyr1246/1252; Rat: Tyr1246/1252

P-peptide - +

P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using NMDA/NR2A/B (Phospho-Tyr1246/1252) antibody. Immunofluorescence analysis of HuvEc cells, using NMDA/NR2A/B (Phospho-Tyr1246/1252) antibody.