• Catalog Number:

  E1A0857A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human CDK7 around the phosphorylation site of threonine 170(A-Y-TP-H-Q).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  P50613

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

• Other Names:

  39 kDa protein kinase, CAK, CAK1, CDK-activating kinase, CDKN7, CR4 protein kinase, CRK4, Cell division protein kinase 7, EC 2.7.11.22, EC 2.7.11.23, MO15, MPK-7, P39 Mo15, Protein-tyrosine kinase MPK-7, STK1, TFIIH basal complex kinase subunit, kinase Cdk7

• Specificity Sensitivity:

  CDK7 (Phospho-Thr170) antibody detects endogenous levels of CDK7 only when phosphorylated at threonine 170.

• References:

  J. Matt Kim, Biol Reprod, May 2001; 64: 1400. Ann Yee, Cancer Res., Dec 1995; 55: 6058 - 6062. Saya Ito. Genes Cells, Oct 2004; 9: 983 - 992.

• All Sites:

  Human: Thr170; Mouse: Thr170

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CDK7 (Phospho-Thr170) antibody. Western blot analysis of extracts from HeLa cells, treated with Calyculin A (50nM, 30mins), using CDK7 (Phospho-Thr170) antibody.