• Catalog Number:

  E1A0809A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human PTP1B around the phosphorylation site of serine 50 (D-V-SP-P-F).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  P18031

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

• Other Names:

  CPTP1, EC 3.1.3.48, PTN1, PTP-1B, PTP-HA2, PTPN1, Protein-protein-tyrosine phosphatase HA2, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase, non-receptor type 1

• Specificity Sensitivity:

  PTP1B (Phospho-Ser50) antibody detects endogenous levels of PTP1B only when phosphorylated at serine 50.

• References:

  Gang Xu, J. Biol. Chem., Dec 2002; 277: 49989 - 49997. Yinges Yigzaw, J. Biol. Chem., Jan 2003; 278: 284 - 288. Jinseol Rhee, J. Biol. Chem., Feb 2001; 276: 6640 - 6644. Fawaz G. Haj, Science, Mar 2002; 295: 1708.

• All Sites:

  Human: Ser50; Mouse: Ser50

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using PTP1B (Phospho-Ser50) antibody. Western blot analysis of extracts from COS7 cells, treated with UV (30mins), using PTP1B (Phospho-Ser50) antibody.