• Catalog Number:

  E1A0738A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human SHIP1 around the phosphorylation site of tyrosine 1021 (P-L-YP-G-S).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  Q92835

• Applications:

  WB: 1:500~1:1000 ELISA: 1:40000

• Other Names:

  EC 3.1.3.n1; inositol polyphosphate-5-phosphatase of 145 kDa; INPP5D; p150Ship; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2-containing inositol 5'-phosphatase 1; SHIP-1; SHIP1; SIP-145

• Specificity Sensitivity:

  SHIP1 (Phospho-Tyr1021) antibody detects endogenous levels of SHIP1 only when phosphorylated at tyrosine 1021.

• References:

  Drayer A.L., Biochem. Biophys. Res. Commun. 225:243-249(1996). Ware M.D., Blood 88:2833-2840(1996). Kavanaugh W.M., Curr. Biol. 6:438-445(1996). --------------------------------------------------------------------

• All Sites:

  Human: Tyr1021; Mouse: Tyr1020

Western blot analysis of extracts from HepG2 cells, treated with TNF (200ng/ml, 30mins), using SHIP1 (Phospho-Tyr1021) antibody.