• Catalog Number:

  E1A0592A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 8 (A-P-SP-P-Q).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Mouse, Rat

• SwissProtNo:

  P24529

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

• Other Names:

  EC 1.14.16.2, TH isoform 3, TH isoform a, TH-4, TY3H, TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, tyrosine hydroxylase

• Specificity Sensitivity:

  Tyrosine Hydroxylase (Phospho-Ser8) antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 8.

• References:

  Marco Cosentino, Blood, Jan 2007; 109: 632 - 642. ZG Xue, J. Neurosci., Mar 1988; 8: 806. L Iacovitti, J. Neurosci., Apr 1987; 7: 1264. DM Kuhn, J. Biol. Chem., Apr 1990; 265: 5780 - 5786.

• All Sites:

  Mouse: Ser8; Rat: Ser8

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Tyrosine Hydroxylase (Phospho-Ser8) antibody. Western blot analysis of extracts from HepG2 cells, treated with Anisomycin (25ug/ml, 30mins), using Tyrosine Hydroxylase (Phospho-Ser8) antibody.