• Catalog Number:

  E1A0585A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human TIE2 around the phosphorylation site of tyrosine 1108 (T-L-YP-E-K).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  Q02763

• Applications:

  WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

• Other Names:

  Angiopoietin 1 receptor precursor, CD202b antigen, EC 2.7.10.1, HYK, P140 TEK, TEK, TIE-2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, kinase TIE2

• Specificity Sensitivity:

  TIE2 (Phospho-Tyr1108) antibody detects endogenous levels of TIE2 only when phosphorylated at tyrosine 1108.

• References:

  Ziegler S.F., Oncogene 8:663-670(1993). Zhang Z., Protein Sci. 13:2819-2824(2004). Sjoeblom T., Science 314:268-274(2006).

• All Sites:

  Human: Tyr1108; Mouse: Tyr1106

Western blot analysis of extracts from NIH-3T3 cells, using TIE2 (Phospho-Tyr1108) antibody.