• Catalog Number:

  E1A0542A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Parkin around the phosphorylation site of serine 131 (K-D-SP-P-P).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  O60260

• Applications:

  IHC: 1:50~1:100 ELISA: 1:10000

• Other Names:

  EC 6.3.2.-, PARK2, PRKN, PRKN2, Parkinson disease protein 2, Parkinson juvenile disease protein 2, ubiquitin E3 ligase PRKN

• Specificity Sensitivity:

  Parkin (Phospho-Ser131) antibody detects endogenous levels of Parkin only when phosphorylated at serine 131.

• References:

  J. Menéndez, Hum. Mol. Genet., Jul 2006; 15: 2045 - 2058. Miratul M.K. Muqit, Hum. Mol. Genet., Jan 2004; 13: 117 - 135. Kenny K. K. Chung, Sci. Aging Knowl. Environ., Apr 2004; 2004: or11. Se Jung Kim, J. Biol. Chem., Oct 2003; 278: 41890 - 41899.

• All Sites:

  Human: Ser131; Mouse: Ser131

P-peptide - + Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using Parkin (Phospho-Ser131) antibody.