• Catalog Number:

  E1A0503A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Lamin A/B (lamin A/C) around the phosphorylation site of serine 392 (S-P-SP-P-T).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P02545

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

• Other Names:

  70 kDa lamin, LAMA, LMN1, LMNA

• Specificity Sensitivity:

  Lamin A/B (Phospho-Ser392) antibody detects endogenous levels of Lamin A/B (lamin A/C) only when phosphorylated at serine 392.

• References:

  Dan Constantinescu, Stem Cells, Jan 2006; 24: 177 - 185. Jan Lammerding, J. Biol. Chem., Sep 2006; 281: 25768 - 25780. Carmen Ivorra, Genes & Dev., Feb 2006; 20: 307 - 320. Dayle McClintock, PNAS, Feb 2006; 103: 2154 - 2159.

• All Sites:

  Human: Ser392; Mouse: Ser392; Rat: Ser392

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Lamin A/B (Phospho-Ser392) antibody. Western blot analysis of extracts from HeLa cells, using Lamin A/B (Phospho-Ser392) antibody.

P-peptide - + Immunofluorescence analysis of HeLa cells, using Lamin A/B (Phospho-Ser392) antibody.