• Catalog Number:

  E1A0081A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human; Mouse; Rat

• SwissProtNo:

  P16885

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

• Other Names:

  1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2; EC 3.1.4.11; phospholipase C-gamma-2; PLC-gamma2; PLC-IV

• Specificity Sensitivity:

  PLCG2 (Phospho-Tyr753) antibody detects endogenous levels of PLCG2 only when phosphorylated at tyrosine 753.

• References:

  Ohta S., FEBS Lett. 242-31-35(1988). Kemmer D., BMC Genomics 7:48-48(2006). Martin J., Nature 432:988-994(2004).

• All Sites:

  Human: Tyr753; Mouse: Tyr753; Rat: Tyr753

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using PLCG2 (Phospho-Tyr753) antibody. Western blot analysis of extracts from HepG2 cells, treated with Na3VO4 (0.3mMl, 40mins), using PLCG2 (Phospho-Tyr753) antibody.