• Catalog Number:

  E1A8292A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human APLP2 around the phosphorylation site of tyrosine 755 (P-T-YP-K-Y).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%);Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)

• SwissProtNo:

  Q06481

• Applications:

  IHC: 1:50~1:100 ELISA: 1:20000

• Other Names:

  Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH; APPL2; CDEBP; CDEI-box binding protein

• Specificity Sensitivity:

  APLP2 (Phospho-Tyr755) antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755.

• References:

  Sprecher C.A., Biochemistry 32:4481-4486(1993). Wasco W., Nat. Genet. 5:95-99(1993). von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

• All Sites:

  Human: Tyr755; Mouse: Tyr687; Rat: Tyr757

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using APLP2 (Phospho-Tyr755) antibody. APLP2 (Phospho-Tyr755) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.