• Catalog Number:

  E1A8239A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human FRS2 around the phosphorylation site of tyrosine 436 (L-N-YP-I-Q).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%)

• SwissProtNo:

  Q8WU20

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

• Other Names:

  FGFR signalling adaptor; FGFR signalling adaptor SNT-1; SNT-1; SNT2; SUC1-associated neurotrophic factor target; Suc1-associated neurotrophic factor target

• Specificity Sensitivity:

  FRS2 (Phospho-Tyr436) antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436.

• References:

  Xu H., J. Biol. Chem. 273:17987-17990(1998). Meakin S.O., J. Biol. Chem. 274:9861-9870(1999). Dhalluin C., Mol. Cell 6:921-929(2000).

• All Sites:

  Human: Tyr436; Mouse: Tyr436

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using FRS2 (Phospho-Tyr436) antibody. Western blot analysis of extracts from COS cells, using FRS2 (Phospho-Tyr436) antibody.