• Catalog Number:

  E1A8195A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Trk B around the phosphorylation site of tyrosine 706 and tyrosine 707 (T-D-YP-YP-R-V).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%);Rat (Identities = 100%, Positives = 100%)

• SwissProtNo:

  Q16620

• Applications:

  IHC: 1:50~1:100 ELISA: 1:10000

• Other Names:

  BDNF/NT-3 growth factors receptor precursor; EC 2.7.10.1; GP145-TrkB; GP145-TrkB/GP95-TrkB; kinase TrkB; NTRK2; Trk-B; TrkB tyrosine kinase

• Specificity Sensitivity:

  Trk B (Phospho-Tyr706+Tyr707) antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.

• References:

  Nakagawara A., Genomics 25:538-546(1995). Shelton D.L., J. Neurosci. 15:477-491(1995). Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).

• All Sites:

  Human: Tyr706+Tyr707; Mouse: Tyr705+Tyr706; Rat: Tyr705+Tyr706

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Trk B (Phospho-Tyr706+Tyr707) antibody. Trk B (Phospho-Tyr706+Tyr707) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.