• Catalog Number:

  E1A8194A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Trk A around the phosphorylation site of tyrosine 757 (E-V-YP-A-I).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 90%, Positives = 100%);Rat (Identities = 90%, Positives = 100%)

• SwissProtNo:

  P04629

• Applications:

  IHC: 1:50~1:100 ELISA: 1:10000

• Other Names:

  EC 2.7.10.1; High affinity nerve growth factor receptor precursor; kinase TrkA; NTRK1; p140-TrkA; Slow nerve growth factor receptor; TRK; Trk-A; TRK1 transforming tyrosine kinase protein; TRKA

• Specificity Sensitivity:

  Trk A (Phospho-Tyr757) antibody detects endogenous levels of Trk A only when phosphorylated at tyrosine 757.

• References:

  Martin-Zanca D., Mol. Cell. Biol. 9:24-33(1989). Shelton D.L., J. Neurosci. 15:477-491(1995). The MGC Project Team, Genome Res. 14:2121-2127(2004).

• All Sites:

  Human: Tyr757; Mouse: Tyr760; Rat: Tyr760

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Trk A (Phospho-Tyr757) antibody. Trk A (Phospho-Tyr757) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.