• Catalog Number:

  E1A8042A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human IGF1R around the phosphorylation site of tyrosine 1346 (Q-P-YP-A-H).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%);Rat (Identities = 100%, Positives = 100%)

• SwissProtNo:

  P08069

• Applications:

  IHC: 1:50~1:100 ELISA: 1:40000

• Other Names:

  CD221; EC 2.7.10.1; IGF1R; Insulin-like growth factor I receptor precursor; kinase IGF1R

• Specificity Sensitivity:

  IGF1R (Phospho-Tyr1346) antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346.

• References:

  Ullrich A., EMBO J. 5:2503-2512(1986). Abbot A.M., J. Biol. Chem. 267:10759-10763(1992). The MGC Project Team;Genome Res. 14:2121-2127(2004).

• All Sites:

  Human: Tyr1346; Mouse: Tyr1352; Rat: Tyr1349

P-peptide - +

Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF1R (Phospho-Tyr1346) antibody. IGF1R (Phospho-Tyr1346) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.