• Catalog Number:

  E1A7095A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human GluR1 around the phosphorylation site of serine 863 (R-N-SP-G-A).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P42261

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

• Alter Name:

  GLR1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor 1 precursor, Glutamate receptor ionotropic, AMPA 4

• Specificity Sensitivity:

  GluR1 (phospho-Ser863) antibody detects endogenous levels of GluR1 only when phosphorylated at serine 863.

• References:

  Davide Ragozzino, J. Neurosci., Oct 2006; 26: 10488 - 10498. Raymond Dingledine, Pharmacol. Rev., Mar 1999; 51: 7. E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107. Jianqun Wu, J Neurophysiol, Jun 2006; 95: 3519 - 3527.

• All Sites:

  Human: Ser863; Mouse: Ser863; Rat: Ser863

P-peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR1 (phospho-Ser863) antibody.

Western blot analysis of extracts from HeLa cells treated with PMA (125ng/ml, 30mins), using GluR1 (phospho-Ser863) antibody (Line 1 and 2).