• Catalog Number:

  E1A1080A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human JAK3 around the phosphorylation site of tyrosine 785 (S-D-YP-E-L).

• Purification:

  The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P52333

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

• Other Names:

  EC 2.7.10.2, JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3 EC 2.7.10.2, JAK-3, JAK3, Janus kinase 3, L-JAK, Leukocyte janus kinase, kinase Jak3

• Specificity Sensitivity:

  JAK3 (Phospho-Tyr785) antibody detects endogenous levels of JAK3 only when phosphorylated at tyrosine 785.

• References:

  Kawamura M., Proc. Natl. Acad. Sci. U.S.A. 91:6374-6378(1994). Lai K.S., J. Biol. Chem. 270:25028-25036(1995). Endo K., FEBS Lett. 477:55-61(2000). ----------------------------------------------------------------------------

• All Sites:

  Human: Tyr785; Mouse: Tyr996; Rat: Tyr781

Western blot analysis of extracts from Jurkat cells, using JAK3 (Phospho-Tyr785) antibody diluted at 1:1000.

Immunohistochemistry analysis of human brain tissue, using JAK3 (Phospho-Tyr785) antibody diluted at 1:100.