• Catalog Number:

  E1A1070A-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Inositol 1,4,5-trisphosphate R1 around the phosphorylation site of serine 1598/1588 (R-D-SP-V-L).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%);Rat (Identities = 100%, Positives = 100%)

• SwissProtNo:

  Q14643

• Applications:

  IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

• Other Names:

  IP3 receptor isoform 1, IP3R, ITPR1, Inositol 1,4,5-trisphosphate receptor type 1, InsP3R1, Type 1 InsP3 receptor, Type 1 inositol 1,4,5- trisphosphate receptor

• Specificity Sensitivity:

  Inositol 1,4,5-trisphosphate R1 (Phospho-Ser1598/1588) antibody detects endogenous levels of Inositol 1,4,5-trisphosphate R1 only when phosphorylated at serine 1598/1588.

• References:

  Mitsuharu Hattori, J. Biol. Chem., Mar 2004; 279: 11967 - 11975. MA Dent, Development, Mar 1996; 122: 1029. Henk Sipma, J. Biol. Chem., Apr 1999; 274: 12157.

• All Sites:

  Human: Ser1598; Mouse: Ser1588; Rat: Ser1589

P-peptide - +

P-peptide - + Immunohistochemistry analysis of paraffin-embedded human cervix tissue using Inositol 1,4,5-trisphosphate R1 (Phospho-Ser1598/1588) antibody. Immunofluorescence analysis of A549 cells, using Inositol 1,4,5-trisphosphate R1 (Phospho-Ser1598/1588) antibody.

Inositol 1,4,5-trisphosphate R1 (Phospho-Ser1598/1588) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.