• Catalog Number:

  E1A1020A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human APC1 around the phosphorylation site of serine 688 (S-L-SP-P-V).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody againstnon-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse

• SwissProtNo:

  Q9H1A4

• Applications:

  IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

• Other Names:

  ANAPC1, ANC1, Anaphase promoting complex subunit 1, Cyclosome subunit 1, Mitotic checkpoint regulator, Protein Tsg24, TSG24

• Specificity Sensitivity:

  APC1 (Phospho-Ser688) antibody detects endogenous levels of APC1 only when phosphorylated at serine 688.

• References:

  Yashi Ahmed, Development, Apr 2002; 129: 1751. Praveen Kumar, J. Biol. Chem., Sep 2005; 280: 31783 - 31791. Rebecca A. Green, Mol. Biol. Cell, Oct 2005; 16: 4609 - 4622. Brian R. Thornton, Genes & Dev., Feb 2006; 20: 449 - 460.

• All Sites:

  Human: Ser688; Mouse: Ser688

P-peptide - +

P-peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using APC1 (Phospho-Ser688) antibody. Immunofluorescence analysis of COS7 cells, using APC1 (Phospho-Ser688) antibody.