• Catalog Number:

  E1A0076A-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human Lyn around the phosphorylation site of tyrosine 507 (G-Q-YP-Q-Q).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P07948

• Applications:

  WB: 1:500~1000 IHC: 1:50~100 ELISA: 1:1000

• Alter Name:

  ONCOGENE LYN, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

• Specificity Sensitivity:

  Lyn (Phospho-Tyr507) antibody detects endogenous levels of Lyn only when phosphorylated at tyrosine 507.

• References:

  Fu-Jun Li, Blood, Apr 2005; 105: 3295 - 3302. Naohiro Tsuyama, AACR Meeting Abstracts, Apr 2005; 2005: 1083. Antonella Contri, J. Clin. Invest., Feb 2005; 115: 369 - 378. Wenbin Xiao, J. Immunol., Nov 2005; 175: 6885 - 6892.

• All Sites:

  Human: Tyr507; Mouse: Tyr507; Rat: Tyr508

P-peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using Lyn (Phospho-Tyr507) antibody (#A0076).

Western blot analysis of extracts from K562 cells treated with H2O2 (100uM, 30mins), using Lyn (Phospho-Tyr507) antibody (#A0076).