• Catalog Number:

  E1A0062A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human CCR5 around the phosphorylation site of serine 349 (E-I-SP-V-G).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human

• SwissProtNo:

  P51681

• Applications:

  WB: 1:500~1000 ELISA: 1:5000

• Alter Name:

  C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CD195 antigen, CHEMR13, CKR5, CMKBR5, HIV-1 fusion co-receptor, MIP-1 alpha receptor

• Specificity Sensitivity:

  CCR5 (Phospho-Ser349) antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349.

• References:

  Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875. Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198. Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259. H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281.

• All Sites:

  Human: Ser349

Western blot analysis of extracts from HeLa cells treated with PMA (125ng/ml, 30mins), using CCR5 (Phospho-Ser349) antibody.