• Catalog Number:

  E1A0011A-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized phosphopeptide derived from human GABA-RB around the phosphorylation site of serine 434 (R-A-SP-Q-L).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P18505

• Applications:

  WB: 1:500~1000 IHC: 1:50~100 ELISA: 1:40000

• Alter Name:

  GABA(A) receptor, GABA(A)R beta-1, GBRB1, Gamma-aminobutyric-acid receptor beta-1 subunit precursor

• Specificity Sensitivity:

  GABA-RB (phospho-Ser434) antibody detects endogenous levels of GABA-RB only when phosphorylated at serine 434.

• References:

  Robnet T. Kerns, J. Neurosci., Mar 2005; 25: 2255 - 2266. Masaru Moriyama, Mol. Cancer Ther., Feb 2003; 2: 199. Jan A. Gorter J. Neurosci., Oct 2006; 26: 11083 - 11110. Fraser J. Sim J. Neurosci., Nov 2006; 26: 12544 - 12555.

• All Sites:

  Human: Ser434; Mouse: Ser434; Rat: Ser434

P-peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using GABA-RB (phospho-Ser434) antibody.

Western blot analysis of extracts from cos7 cells, using GABA-RB (phospho-Ser434) antibody.