• Catalog Number:

  E1A8476B-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized non-phosphopeptide derived from human SirT1 around the phosphorylation site of serine 47 (E-R-SP-P-G).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%);

• SwissProtNo:

  Q96EB6

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

• Other Names:

  hSIR2; hSIRT1; NAD-dependent deacetylase sirtuin 1; SIR1; SIR2-like protein 1; SIR2L1; sirtuin 1

• Specificity Sensitivity:

  SirT1 (Ab-47) antibody detects endogenous levels of total SirT1 protein.

• References:

  Rogers J., Nature 429:375-381(2004). Weinberg R.A., Cell 107:149-159(2001). Sinclair D.A., Nature 425:191-196(2003). ------------------------------------------------------------------------------------------------------------------------------------------

Peptide - +

Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using SirT1 (Ab-47) antibody. Western blot analysis of extracts from K562 cells, using SirT1 (Ab-47) antibody.