• Catalog Number:

  E1A7122B-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 636 or serine 639 (M-S-P-K-S).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P35568

• Applications:

  WB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:20000

• Alter Name:

  IRS-1, IRS1, Insulin receptor substrate-1

• Specificity Sensitivity:

  IRS-1 (Ab-636/639) antibody detects endogenous levels of total IRS-1 protein.

• References:

  Ozes ON, et al. (2001) Proc Natl Acad Sci USA; 98(8): 4640-4645. Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76. Kadowaki T, et al. (2000) J Clin Invest; 106(4): 459-465. Ozes ON, et al. (2001) Proc Natl Acad Sci USA; 98(8): 4640-4645. Szanto I, et al. (2000) Proc Natl Acad Sci USA; 97(5): 2355-2360.

Peptide - +

Immunohistochemical analysis of paraffin-embedded human brain, using IRS-1 (Ab-636/639) antibody. Western blot analysis of extracts from K562 cells, using IRS-1 (Ab-636/639) antibody.