• Catalog Number:

  E1A7120B-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307 (T-E-S-I-T).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P35568

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

• Alter Name:

  Insulin receptor substrate 1,IRS1 CORONARY ARTERY DISEASE

• Specificity Sensitivity:

  IRS-1 (Ab-307) antibody detects endogenous levels of tota IRS-1 protein.

• References:

  Philip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077. Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843. Ana González-García, et al. (2002) J. Biol. Chem; 277: 1500-1508. Ulrike Krause, et al. (2002) Eur. J. Biochem; 269: 3751.

Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1 (Ab-307) antibody (#B7120).

Western blot analysis of extracts from A431 cells, using IRS-1 (Ab-307) antibody (#B7120, Line 1 and 2).