Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Store at -20℃/1 year
class="eg_cn_title"Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human SHP-1 around the phosphorylation site of tyrosine 536 (S-E-Y-G-N).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SHP-1 (Ab-536) antibody detects endogenous levels of total SHP-1 protein.
References:
Laura A. Maile, Mol. Biol. Cell, Sep 2003; 14: 3519.
Tony Avril, J. Immunol., Dec 2004; 173: 6841 - 6849.
Hong Xu, J. Biol. Chem., Jul 1998; 273: 17987.
Gregory Bix, Blood, Dec 2006; 10: 1182.
Peptide - +
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-1 (Ab-536) antibody (#B0026).
Western blot analysis of extracts from NIH/3T3 cells, using SHP-1 (Ab-536) antibody (#B0026, Line 1 and 2).