• Catalog Number:

  E1A0059B-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized non-phosphopeptide derived from human Caspase 8 around the phosphorylation site of serine 347 (C-P-S-L-A).

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  Q14790

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

• Alter Name:

  Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog

• Specificity Sensitivity:

  Caspase 8 (Ab-347) antibody detects endogenous levels of total Caspase 8 protein.

• References:

  Daniel R. Beisner, J. Immunol., Sep 2005; 175: 3469 - 3473. Peter J. Wild, Mol. Cancer Ther., Apr 2005; 4: 516 - 528. A.V. TIMOFEEVA, Ann. N.Y. Acad. Sci., Dec 2006; 1091: 319 - 335. Leon Tourian, J. Cell Sci., Dec 2004; 117: 6459 - 6471.

Peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 8 (Ab-347) antibody (#B0059).

Western blot analysis of extracts from NIH/3T3 cells treated with TNF-α(20ng/ml,30min), using Caspase 8 (Ab-347) antibody (#B0059, Line 1 and 2).