• Catalog Number:

  E1A0320L-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human MMP12.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human

• SwissProtNo:

  P39900

• Applications:

  WB: 1:500~1:1000 ELISA: 1:20000

• Other Names:

  Macrophage metalloelastase [Precursor], EC 3.4.24.65, HME, Matrix metalloproteinase-12, MMP-12, Macrophage elastase, ME, MMP12, HME

• Specificity Sensitivity:

  MMP12 (Cleaved-Glu106) antibody detects endogenous levels of fragment of activated MMP12 resulting from cleavage adjacent to Glu106.

• References:

  Shapiro S.D., J. Biol. Chem. 268:23824-23829(1993). Gronski T.J. Jr., J. Biol. Chem. 272:12189-12194(1997). Lang R., J. Mol. Biol. 312:731-742(2001).

Western blot analysis of extracts from NIH-3T3 cells, treated with etoposide (25uM, 1hour), using MMP12 (Cleaved-Glu106) antibody.